Risk Of Depression From Insulin Resistance,Analyze It

Insulin plays an important role in diabetes, there is also complaint of constant sadness, hopelessness, lethargy, and loss of appetite

In this disease, many vital organs gradually weaken or deteriorate. Now new research shows that the body's resistance to insulin doubles the risk of developing severe depression. The findings are published in the American Journal of Psychiatry.

Insulin resistance occurs when muscle, fat, and liver cells do not respond properly to insulin and cannot use blood glucose for release.

"If you have insulin resistance, you may be twice as likely as the general population, even if you have never had such complaints before," said Ratail Rasgun, professor of psychology and behavioral science at the University of Amsterdam Medical Center. Symptoms include persistent sadness, depression, drowsiness, insomnia, and loss of appetite. However, factors such as childhood accidents and the death of a loved one can also contribute to these inevitable illnesses. But insulin resistance can be prevented and achieved through diet, exercise, and medication. Numerous studies confirm that one in three people suffer from insulin resistance and are unaware of it.

This condition is not caused by the pancreas' ability to release insulin into the bloodstream, as is the case with type 1 diabetes. On the contrary, this condition is caused by the alertness to regulate this hormone in the cells of the whole body. In fact, the function of insulin is to direct cells to process glucose (which is produced by food and the liver) in the blood.

Each cell uses glucose as fuel, and each cell has receptors on its surface that bind to insulin and signal its ability to be absorbed.

Why and how is the problem?

The reality is that the number of people with insulin resistance is increasing around the world. The main reason for this is a high-calorie intake, lack of exercise, stress and not getting enough sleep due to various reasons. As a result, the insulin receptor is unable to bind to insulin properly. However, blood sugar remained high.

Once the sugar level reaches a certain level, type 2 diabetes occurs, which can be treated. But if not treated properly, apart from diseases related to the heart and kidney, it can also cause amputation. This has a huge impact on overall health.

Insulin resistance has been linked to a variety of mental illnesses. For example, it has been found that 40 percent of people with mood disorders have insulin resistance. But the question still remains unresolved whether it was caused by some event or whether there were elements involved. A long study was done to find out.

How did you study

Researchers obtained data from 3,000 people in the Netherlands who were involved in the depression and anxiety study. This study focused on the causes and consequences of depression. When she registered for the study, she had no complaints of depression or anxiety. The mean age of the participants was 41 years.

The researchers found three signs of insulin resistance in the parents -- abdominal glucose levels, waist size, and high-density lipoprotein (HDL) or good cholesterol in the blood. Then, for nine years, they looked at the risk of developing depression.

There was a moderate increase in insulin resistance, as measured by the triglycerides to HDL ratio, which corresponded to an 89 percent increase in the rate of new cases of depressive disorder.

Similarly, for every five-centimeter increase in belly fat, the risk of depression was 11 percent higher. Thus, with an increase in fasting plasma glucose to 18 milligrams per deciliter of blood, the risk of depression was found to be 37 percent higher.